While neonatal jaundice – or hyperbilirubinemia – occurs in almost all babies, it is a cause of concern for caregivers and anxiety for families. If not treated in time, neonatal jaundice can lead to permanent brain damage1 . Screening for jaundice by visual assessment can lead to an overestimation of risk, which means unnecessary lab tests. This blood draw (total serum bilirubin testing (TsB)) requires a heel prick, which is painful for the baby and costly for the hospital. Visual assessment can also lead to an underestimation of risk, which could result in a failure to obtain necessary lab tests. That’s why transcutaneous bilirubin testing (TcB) has grown rapidly in the past few years as a standard practice in hospitals to identify at-risk infants. But even TcB has presented challenges in terms of human error and time consumption. Until now.